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1.
Article | IMSEAR | ID: sea-223162

ABSTRACT

Background: Despite acne being a common dermatological problem, there is a paucity of literature addressing the knowledge, attitude and practice about it. Aims/Objectives: To find out what patients know about acne, its cause and treatment, as well as myths, misconceptions and attitude towards it. Methods: A cross-sectional, descriptive questionnaire-based study on acne patients at Maharana Bhupal Hospital, RNT Medical College, Udaipur, Rajasthan, India. Results: Most (84.8%) patients belonged to the age group of 16–25 years. The majority (63.9%) presented 12 months after the onset of acne. More than half had average knowledge, a positive attitude and good practices, related significantly to gender and education. Limitations: A standardized questionnaire suitable for all dialects and regional languages would have yielded more uniform results. Conclusion: Study revealed that acne patients still need to acquire accurate, adequate and easily accessible information to seek timely and appropriate treatment, and alleviate their psychological suffering.

2.
Indian J Ophthalmol ; 2023 Jun; 71(6): 2455-2459
Article | IMSEAR | ID: sea-225121

ABSTRACT

Purpose: To report on the microbiological profile and antibiotic sensitivity patterns of infectious keratitis at a tertiary center in central India. Methods: The suspected case of severe keratitis underwent microbiological culture and identification using the VITEK 2 technique. Antibiotic susceptibility for different sensitivity and resistance patterns was analyzed. Demographics, clinical profile, and socioeconomic history was also documented. Results: Culture was positive in 233/455 (51.2%) patients. Pure bacterial growth was present in 83 (35.62%) patients and pure fungus was present in 146 (62.66%) patients. The most common bacterial cause of infectious keratitis was Pseudomonas followed by Staphylococcus and Bacillus. Pseudomonas showed 65%–75% resistance against levofloxacin, ceftazidime, imipenem, gentamycin, ciprofloxacin, and amikacin. Staphylococcus showed 65%–70% resistance against levofloxacin, erythromycin, and ciprofloxacin, with Streptococcus being 100% resistant to erythromycin. Conclusion: This study highlights the current trend of microbiological profiles of infectious keratitis and their antibiotic susceptibility at a rural setup in central India. Fungal predominance and increased resistance against the commonly used antibiotics were noted.

3.
Indian J Ophthalmol ; 2023 Jun; 71(6): 2500-2503
Article | IMSEAR | ID: sea-225087

ABSTRACT

Purpose: Glaucoma is the second leading cause of blindness worldwide, affecting more than 64 million people aged 40–80. The best way to manage primary open?angle glaucoma (POAG) is by lowering the intraocular pressure (IOP). Netarsudil is a Rho kinase inhibitor, the only class of antiglaucoma medications that reorganizes the extracellular matrix to improve the aqueous outflow through the trabecular pathway. Methods: An open?label, real?world, multicentric, observation?based 3?month study was performed for assessing the safety and ocular hypotensive efficacy of netarsudil ophthalmic solution (0.02% w/v) in patients with elevated IOP. Patients were given netarsudil ophthalmic solution (0.02% w/v) as a first?line therapy. Diurnal IOP measurements, best?corrected visual acuity, and adverse event assessments were recorded at each of the five visits (Day?1: screening day and first dosing day; subsequent observations were taken at 2 weeks, 4 weeks, 6 weeks, and 3 months). Results: Four hundred and sixty?nine patients from 39 centers throughout India completed the study. The mean IOP at baseline of the affected eyes was 24.84 ± 6.39 mmHg (mean ± standard deviation). After the first dose, the IOP was measured after 2, 4, and 6 weeks, with the final measurement taken at 3 months. The percentage reduction in IOP in glaucoma patients after 3 months of once?daily netarsudil 0.02% w/v solution use was 33.34%. The adverse effects experienced by patients were not severe in the majority of cases. Some adverse effects observed were redness, irritation, itching, and others, but only a small number of patients experienced severe reactions, as reported in a decreasing order: redness > irritation > watering > itching > stinging > blurring. Conclusion: We found that netarsudil 0.02% w/v solution monotherapy when used as the first?line treatment in primary open?angle glaucoma and ocular hypertension was both safe and effective.

4.
Article | IMSEAR | ID: sea-217420

ABSTRACT

In today’s scenario accelerating cost of health significantly impact the health of people and the populace creat-ing a monetary burden on poor households. One of the key concerns while tackling healthcare disparities is out-of-pocket expenses (OOPE). Providing financial safety and provide universal coverage to the entire popu-lace are the main goal of health schemes. Health policies in India are based on equity prioritising the needs of the poor and underprivileged. Likewise, there is a discrepancy in the consistency of information and knowledge regarding the scheme among the beneficiaries. A review was created to help medical and nursing professionals to gain comprehensive knowledge of various health schemes. We tried to give an overview of various health schemes including Ayushman Bharat Yojana, Aam Aadmi Bima Yojana (AABY), Pradhan Mantri Suraksha Bima Yojana (PMSBY), Rashtriya Swasthya BimaYojana (RSBY), Central Government Health Scheme (CGHS), Employees State Insurance Scheme (ESIC), Employee Health Scheme and various state-level health schemes. include, Yeshasvini Health Insurance Scheme, Mahatma Jyotiba Phule Jan Arogya Yojana, Chief Min-ister Comprehensive Health Insurance Scheme, Mukhyamantri Amrutum Yojana, Karunya Health Scheme, Awaz Health Insurance Scheme, Telangana State Govt Employees and Journalist Health Scheme, Dr Ysr Aarog-yastri Health Care Trust, Mukhyamantri Chiranjeevi Yojana, Rajasthan Government Health Scheme (RGHS), and Aarogya Raksha.

5.
Article | IMSEAR | ID: sea-216340

ABSTRACT

People with type 2 diabetes mellitus (T2DM) have a higher risk of developing chronic liver disease (CLD) and its complications. T2DM, obesity, and insulin resistance are all strongly associated with nonalcoholic fatty liver disease (NAFLD). Conversely, people suffering from cirrhosis have reduced glucose tolerance in approximately 60% of cases, diabetes in 20% of cases, and insulin-mediated glucose clearance is lowered by 50% as compared with those who do not have cirrhosis. An exploratory review was conducted using existing published evidence from clinical studies on dosing and titrations of individual insulin formulations in people with CLD to optimize insulin dosage titration for minimizing hypoglycemia risk. This article discusses current hyperglycemia treatment techniques for patients with CLD as well as the consensus recommendations on insulin use in special populations with T2DM and hepatic impairment. Based on available evidence and expert diabetologists’ recommendations, careful insulin dose titration, customized glycemic targets, and frequent glucose screening are recommended for optimal glycemic management without hypoglycemia in CLD. Long-acting insulin should be avoided or used when short-acting insulin fails to provide adequate glycemic control with raised fasting blood sugar levels. While the patient’s glucose profile is being evaluated, the prandial insulin dose can be lowered by 25% initially. The dose can be titrated based on the patient’s postprandial glycemic expression and whether their food intake meets the Child–Pugh scores A and B categories. Titrating premixed insulins is difficult for patients in class C since their appetite and overall health are constantly compromised and in flux.

6.
Article | IMSEAR | ID: sea-221401

ABSTRACT

Background: The purpose of this study was to assess the accuracy of preoperative CT imaging for predicting pathologic nodal ECE (pECE). To estimate the accuracy of the presence of radiologic extranoda AIM: l extension (rENE) in reference to pathologic extranodal extension (pENE) in patients with oral cavity squamous cell carcinoma (OSCC) MATERIALS AND METHODS: This is a prospective study in GSVM Medical College, LLR & Associated Hospitals, Kanpur (UP). The records of 50 consecutive patients with oral cavity cancer (OCC) who underwent preoperative CT imaging before initial surgical resection and neck dissection between 2020 and 2021 were reviewed. Specimens with pECE had the extent of ECE graded on a scale from 1 to 4. Radiographic ECE was RESULTS: documented in 6 patients (12%), and pECE was observed in 11 (22%). Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 45.4%, 97.4%, 83.6%, and 86.3%, respectively. The sensitivity of radio- graphic ECE increased from 40% for grade 1 to 2 ECE, to 50% for grade 3, and 50% for grade 4. Radiographic ECE criteria of adjacent structure invasion was a better predictor than irregular borders/fat stranding for pECE. Radiographic ECE has poor sensitivity, but excellent spec CONCLUSION:Radiographic ECE criteria ificity for pECE in patients who undergo initial surgical resection. PPV and NPV are reasonable for clinical decision making. The performance of preoperative CT imaging increased as pECE grade increased.

7.
Article | IMSEAR | ID: sea-220218

ABSTRACT

Background: The patient partnership is desirable for the optimal management of comorbidities. This became significant more so during the coronavirus disease 2019 (COVID-19) crisis wherein health infrastructure was overburdened. Objectives?The aim of this study was to estimate the clinicoepidemiological profile, health literacy regarding predisposing risk factors, and disease management in patients with COVID-19-associated mucormycosis (CAMCR). Materials and Methods?A structured questionnaire-based study on randomly chosen 100 microbiologically proven patients of CAMCR, consisting of 38 multiple choice questions, was designed with each answer having a patient and assessor response to it. Results?A male predilection was seen (68%) with rhino-orbital (73%) being the commonest anatomic site. Forty-nine percent of the study participants had pre-existing diabetes of which 62% did not carry out regular blood sugar monitoring and in 18%, blood sugars were controlled prior to COVID-19. Thirty-five percent of patients with mild COVID-19 illness were treated with unwarranted steroids and 56% of patients had fluctuating blood sugar levels, during COVID-19 illness. Seventy-nine percent of patients were not vaccinated against COVID-19, 16% only partially vaccinated. Seventy-one percent of patients were not aware of red flag signs and of mucormycosis with 8% presenting early, on noticing nasal symptoms. Conclusion?This study observed diabetes as the most common comorbidity in patients with CAMCR. A lacuna in the health literacy of diabetics presenting with CAMCR was found. Additionally, knowledge regarding glycemic control during COVID-19 illness with or without the use of steroids and awareness of the “red flag” signs of CAMCR were mostly lacking. Interventions to improve awareness amongst patients with diabetes should help in optimal glycemic control, and avoid potential complications like severe COVID-19 illness, and mucormycosis

8.
J Indian Med Assoc ; 2023 Jan; 121(1): 48-49
Article | IMSEAR | ID: sea-216674

ABSTRACT

Neurological complications in Dengue patients are extremely rare with 0.5-6% incidence including encephalopathy, Guillain Barre Syndrome, Brachial neuritis, Myelitis, Encephalomyelitis. Stroke as a neurological complication is extremely rare with very few cases reported previously. We present the case of a 69-year-old male with Dengue fever where the patient presented with persistent hiccups was found to have pontine infarct.

9.
Rev. bras. cir. cardiovasc ; 38(4): e20210591, 2023.
Article in English | LILACS-Express | LILACS | ID: biblio-1449556
10.
Osteoporosis and Sarcopenia ; : 70-75, 2023.
Article in English | WPRIM | ID: wpr-1002649

ABSTRACT

Objectives@#Graves' disease (GD) is the most common cause of thyrotoxicosis. There are many studies that have evaluated bone mineral density (BMD) in Graves’ disease. However, the strength of a bone also depends on its microarchitecture which can be assessed by various techniques. Trabecular bone score (TBS) is a new method for assessing bone microarchitecture that is non-invasive and easily performed. @*Methods@#The present study was a cross-sectional study that involved 50 patients with active GD and 50 healthy controls. Both groups were subjected to an assessment of biochemical parameters followed by measurement of BMD and TBS on the same dual energy X-ray absorptiometry (DXA) machine. @*Results@#The mean age of patients with active GD (N = 50) was 31.9 ± 10.9 years while that of controls was 31.2 ± 4.9 years (P = 0.640). The female: male ratio was the same for both groups (F = 31, M = 19). The mean lumbar spine BMD, femoral neck BMD, total hip BMD, and distal radius BMD were significantly reduced in GD when compared to that in controls. The mean absolute lumbar spine TBS in GD was 1.263 ± 0.101 while that in controls was 1.368 ± 0.073 (P < 0.001). On multivariate regression analysis, the factors that predicted TBS were serum thyroxine (T4) and L1-L4 BMD. @*Conclusions@#Patients with Graves’ disease had reduced bone density at all sites and degraded microarchitecture. Long-term studies are required to understand the pattern of recovery of bone microarchitecture after the restoration of euthyroidism.

11.
Malaysian Journal of Medicine and Health Sciences ; : 103-109, 2023.
Article in English | WPRIM | ID: wpr-997764

ABSTRACT

@#Introduction: Though there are abundant studies on entrepreneurial intention among students pursuing higher education, there is a lacuna in understanding the entrepreneurial intention of medical students. In the present scenario of increasing unemployment among young medical graduates, this quantitative study was conducted with an aim to examine the level of entrepreneurial intention among medical students and the socio-demographic factors influencing it. Methods: The participants were 318 medical students of a private university in Malaysia. A cross-sectional study design with a validated adapted questionnaire was used to collect data. The data was analysed using descriptive and inferential statistics. Results: A moderately high level of entrepreneurial intention was found among the study population. Regression analysis revealed a statistically significant impact of gender and marital status on their entrepreneurial intention while ethnicity, year of study, household income or educational loan did not have a significant influence. Conclusion: Medical students in Malaysia showed a moderately high inclination towards an entrepreneurial career. Non-economic factors like gender and marital status proved to be stronger influencers of entrepreneurial intention than economic factors. This may help policy makers plan strategies to sustain their entrepreneurial intentions and facilitate for more entrepreneurial activities among young doctors in the futu

12.
Malaysian Journal of Medicine and Health Sciences ; : 196-203, 2023.
Article in English | WPRIM | ID: wpr-996962

ABSTRACT

@#Introduction: In medical education one of the main goal is to facilitate the development of professional identity of medical students. It is influenced by sociocultural factors whose influence has been examined by the empirical scholarship on professional identity research in a robust way. The current research studied the influence of gender, ethnicity and year of study on the professional identity of medical students using a validated instrument. Methods: The quantitative research approach using the cross sectional survey design is adopted in the present study. The instrument for the measurement of professional identity was developed using the items adapted from previous research. Stratified random sampling was used to collect the data from 318 participants. The reliability and construct validity of the instrument was evaluated using Smart PLS 3. Data was analysed, for descriptive and inferential statistics using SPSS version 26. Result: Ethnicity, gender and year of study had an impact on the professional identity of medical students. Indian ethnicity had significantly higher positive influence. The female students had higher professional identity than male medical students. As the students’ progressed to higher level of their training their professional identity progressively decreased. Conclusion: The medical students trained with similar curricular activities and the learning experiences develop different levels of professional identity. The level of professional identity developed by the medical students in deferent gender, ethnicity, and year of study differes. The sociocultural factors need to be considered when designing activities aimed at development of medical students’ professional identity.

13.
Malaysian Journal of Medicine and Health Sciences ; : 182-189, 2023.
Article in English | WPRIM | ID: wpr-996781

ABSTRACT

@#Introduction: People of different cultures perceive health and disease differently. A culturally competent healthcare team is needed to provide quality healthcare. In Asian medical schools, less emphasis is laid on cultural competency training. In this context, the study aims to assess the cultural competency of medical students in Malaysia and to fathom the demographic factors influencing it. Methods: A cross sectional survey was conducted on students from all five years of a Malaysian medical school using an adapted version of Clinical Cultural Competency Questionnaire (CCCQ) to tap the self-perceived knowledge, skills, comfort level in cross-cultural encounters and attitude towards cultural competency. Descriptive and inferential statistics was used to analyse the data. Results: Among the 291 respondents, the cultural competency was found to be significantly different among medical students of different year of study, age, and ethnicity. However, with regards to gender, country of birth or the number of languages spoken, the difference was insignificant. The clinical year students had significantly higher scores on the knowledge, skills, comfort level and attitude domains of cultural competency when compared to the preclinical students. Chinese students’ perception on cultural competence was significantly distinct from Indian and Malay students. Conclusion: Exposure to cross cultural encounters in clinical settings and personal experiences seem to influence cultural competency of the medical students. It provides valuable data to plan for interventions, training and self-development strategies aimed at providing culturally attuned patient centred care.

14.
Malaysian Journal of Medicine and Health Sciences ; : 340-347, 2023.
Article in English | WPRIM | ID: wpr-996581

ABSTRACT

@#Acrylamide (AA) is a chemical substance which is used as a soil stabilizing agent and in the production of copolymers and polymers since 1970. The presence of an AA adduct in food was observed in rats fed with fried food which led to a substantial increase in levels of hemoglobin adduct. Foods that are rich in carbohydrate when prepared at high temperature (above 120 ºC) by baking, toasting, frying, roasting or cooking results in the production of AA by the reaction of the amino acid with glucose present in it. Several studies observed AA toxicity on nervous system, reproductive system, and immune system. To justify this toxicity there is not a clear mechanism described. In this review article the mechanisms of AA toxicity on urogenital system and role of antioxidants against its toxicity has been reviewed. According to previous studies the main factor that induces AA toxicity is oxidative stress. AA treated groups revealed degeneration of the kidney’s epithelial lining and the glomerular tuft. Adverse effect on reproductive system by AA has been evidenced by sperm-head abnormalities, dominant lethal effects, and testicular epithelial tissue degeneration. Therefore, it is advised that modifying of food processing methods and consuming lot of vegetables and fruits containing antioxidants. These antioxidants give us some supports to the cells of our body organs against the AA sources which cause cell defects.

15.
Article | IMSEAR | ID: sea-220646

ABSTRACT

Background: Psychological distress and depression persist in cancer patients, creating an additional burden during treatment and making it more challenging in terms of management and control. There are few studies on the prevalence of psychological distress and depression among cancer patients in the central India. Hence the present study was undertaken to study the prevalence of psychological distress and depression in the adult cancer patients. Method- A total of 271 patients, age between 18 to 75 years, who have been diagnosed with malignancy and receiving treatment from tertiary health care center were included in the study. They were given the Kessler psychological distress scale (K-10), and their responses were recorded. The Beck depression inventory was utilized to determine the severity of depression. Results- Among 271 patients, 112(41.32%) were males and 159(58.67 %) females. Maximum patients were in the age group of 40–60 years (43.17%). Total number of patients suffering from distress was 254(93%) out of 271, most of them (53.87%) had distress score ranging from 25-29 (Moderate). Among 271 patients, 235 (86.71%) patients had mild to severe depression, most of them had depression score between 10-18 (mild). Out of 87 head, neck cancer patients, 74 (85.05%) had depression. High rate of depression found in head neck cancer as compared to other types of cancer. Using the Kessler and Beck Conclusion- depression inventory, this study indicates the high level of distress and sadness among cancer patients. Screening for psychosocial issues and proper treatments are only the beginning of genuinely integrative cancer care strategy.

16.
Article | IMSEAR | ID: sea-219034

ABSTRACT

The peculiarities of anatomic and physiologic features of dromedary camels are elucidated in this review and compared with Bactrian, camels, and other species. Both dromedary and Bactrian camel scrotum varies in length from 10-20 cm and the testes are in the perineal region behind the thighs (like dogs) and weigh from 80-90 gm and length varies from 10-14 cm. Compared to ram and buck, camel epididymis has a higher weight (20-46 g) and has a unique structure called the intra-epithelial glands. Both dromedaries and Bactrian camels do not have seminal vesicles. Male camels have specialized secretory glands behind the ears known as poll glands that are bigger in the Bactrian camels compared to dromedary camels and similar glands are not seen in any of the other domestic species. Camels have a special reproductive behavior during the breeding season known as rut and include extrusion of the soft palate, copious froth from the mouth, gurgling sounds, splashing of urine, increased secretion from the poll glands and loss of appetite with considerable reduction in body weight. Such behaviors are not evidenced by any other domestic species including buffalo. Serum testosterone rises substantially in male camels during rut (2-42 ng/mL) compared to the non-rutting season (0.6-8 ng/mL) and the resultant increase in the size of the testes, number, and functionality of Leydig cells and secretion of poll glands. The serum thyroidal hormones also increase significantly during the rut season. It is concluded that male camels have some special anatomic and physiologic features of reproduction not observed in other domestic species.

17.
Indian J Ophthalmol ; 2022 Nov; 70(11): 3938-3941
Article | IMSEAR | ID: sea-224678

ABSTRACT

Purpose: To determine the stabilization of refraction at 2 weeks following MSICS by comparing the difference in spherical, cylindrical component and also spherical equivalent of refraction of 2 weeks follow-up with that of 6 weeks following surgery. Methods: The difference of spherical, cylindrical component and also spherical equivalent of refraction at 2 weeks and 6 weeks follow-up of 194 eyes that underwent uncomplicated MSICS with implantation of PMMA IOL conducted by a single experienced surgeon were compared to find out the amount of change and its significance was statistically tested by Wilcoxon-Signed Rank Test. Results: The difference in spherical power (0.04 � 0.30), cylinder power (0.03 � 0.40), and spherical equivalent (0.06 � 0.34) were very small and not significant statistically (P-value ?0.05). Conclusion: Necessary spectacle correction can safely be prescribed after 2 weeks following MSICS as subjective refraction stabilizes by that time without undergoing significant change. However, our observation was applicable in patients who had an uneventful cataract surgery without any risk factor, which can delay wound healing or cause poor visual outcome.

18.
Article | IMSEAR | ID: sea-220566

ABSTRACT

Introduction Proximal humeral fractures are now recognized as an increasingly common fracture, accounting for 4%–5% of all fractures and 45% of all humeral fractures [1,2]. It is the third most common fracture, in people above 65 years of age, after fractures of the hip and distal radius [3]. These fractures have a bimodal distribution occurring either in young people after high energy trauma or in those older than 50 years with low- velocity injuries like simple fall [3]. 85% of these fractures are minimally displaced and are effectively treated with immobilization followed by early motion. The remaining 15% of these are either displaced or unstable. These fare poorly with non-operative treatment and are better treated with surgical intervention. Surgical treatment is necessary especially in young patients and active elderly people in order to prevent minimal dislocations of tuberosity or articular surface from compromising the long-term articular function. This study was planned to evaluate the outcome of proximal humerus fractures managed with PHILOS plate after approval by the Institutional Ethical Board. To evaluate the ef?cacy of PHILOS plate in the treatment of Aims And Objectives proximal humeral fractures and assess its functional outcome. To assess any complications that could arise postoperatively Early rehabilitation of the patient Hospital Based Prospective study. Methods And Materials Study Design: Study Period: October 2019 to September 2022. Study is conducted in Department of Orthopaedics, Andhra Medical College, Study Setup: Visakhapatnam. Patients attending emergency/orthopaedic OP and admitted in department of Study Population: orthopaedics in King George Hospital, Visakhapatnam with proximal humerus fractures and are classi?ed according to Neer's Classi?cation 30 patients admitted in the Department of Orthopaedics, King George Hospital, Visakhapatnam Sample Size: with proximal humerus fractures in the above said period. We have included 30 proximal humeral fractures in our Results study. Males dominated and left side is more common than right. Domestic falls are common than road traf?c accidents. 2-part fractures are more common than 3- and 4-part fractures. All of them are treated with PHILOS stable angled plate. Complications like stiffness, screw penetration and super?cial infection occurred in our study which are dealt appropriately. Signi?cantly, we could prevent varus malunion which is notable in our study. Rehabilitation started early with pendulum exercises and could achieve good range of useful movements for most of the cases. Average range of radiological union is 13.5 weeks PHILOS plate, stable, angled construct is used in all our cases and the results evaluation done with . Conclusion Constant Murley score which ranged 54 to 87. Our average score is 67.43 which is in concurrence with few of the studies. The rehabilitation after operation started early with pendulum exercises as soon as the patients compliance within the limits of pain. The range of movements in our study, abduction maximum range obtained is 120 to 150 degrees and forward ?exion 90 to 120 degrees and rotations average score is 7. Though we have few complications like stiffness of shoulder (5), AVN (1), intra- articular screw penetration (1), super?cial infection (1) and subacromial impingement (1), we have dealt with all these complications appropriately. Signi?cantly, varus malunion did not occur in our study

19.
Article | IMSEAR | ID: sea-218686

ABSTRACT

Introduction: Lumbar spondylolisthesis is frequently found in adults as a result of spondylolysis or facet degeneration. The slipped segment produces abnormal positioning of the vertebrae in relation to each other along the spinal column and causes mechanical back pain and compression of neural structures. The initial treatment in most symptomatic patients with lumbar spondylolisthesis is nonoperative supportive care, which consists of a combination of pain medications, bracing, and physical therapy. Surgical intervention is indicated if the symptoms are disabling and they interfere with work despite supportive care, if there is progression of the slippage degree (SD) on serial radiologic examinations, or if there are overt neurological deficits 1,2. Pedicle screw placement is the most popular method in lumbar spinal instrumentation for achieving successful fusion. Recently, to reduce surgical damage to the normal muscular structures during pedicle screw placement, C-arm-guided percutaneous pedicle screw fixation (PPSF) was introduced, and it has become increasingly popular in spinal surgery. Percutaneous transpedicular fixation systems have become more widely used in recent years mainly for the treatment of dorsal, dorsolumbar, and lumbar instability. Aim & Objectives: The present study is aimed at evaluating the functional outcome with percutaneous pedicle screw fixation for spinal fractures& spinal instabilities by free hand technique in patients without neurological deficits. Materials & Methods: The present dissertation is a study of 25 consecutive cases of spinal fractures and spondylolisthesis who attended the orthopaedic emergency or outpatient department of Andhra medical college, Visakhapatnam from 2017 to 2019. All the cases were examined clinically fallowed by radiographic confirmation. Results: In total 25 patients spinal fractures 16 and instability 9, whose mean preoperative ODI scores is 81.04% and the mean postoperative score is 22.6 %. The total postoperative moderate disability patients are15 and minimal disability patients are 10. “PERCUTANEOUS CD FIXATION OF SPINE IN SPINAL FRACTURES/INSTABILITY BY FREEConclusion: HAND TECHNIQUE” is one of the better methods and is suggested for grade 1 & grade 2 spondylolisthesis and spinal fractures, also by which can reduce the morbidity and improve the function.

20.
Article | IMSEAR | ID: sea-216253

ABSTRACT

Introduction: Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of liver disease worldwide. The prevalence of NAFLD varies depending on population studied and type of diagnostic tools used to screen or diagnose the patients. There is a strong relationship between metabolic syndrome components and NAFLD prevalence. This study aims to understand the prevalence of NAFLD along with the associated risk factors and their interaction with other comorbidities among people living with diabetes in Indian context. Materials and methods: It is a retrospective, observational study based on data retrieved from electronic medical records (EMRs) of people living with diabetes from more than 250 individual diabetes centers located in more than 30 cities across 14 states in India. Medical records of 171,996 adults living with diabetes were included in the analysis. The assessment of prevalence of NAFLD in diabetes was done using algorithm based on alanine transaminase (ALT) and aspartate aminotransferase (AST). Results: Overall, 44.48% of people living with diabetes were found to have NAFLD. A significantly higher proportion of males (58.64%) had NAFLD compared to females (36.91%) (p<0.001). Nonalcoholic fatty liver disease prevalence was >50% in seven of the states. People living with diabetes along with dyslipidemia and hypertension had a significantly higher prevalence of NAFLD (p<0.001). Obesity (57.1%), dyslipidemia (59.1%), and hypertriglyceridemia (42.3%) had significantly higher odds of NAFLD among people living with diabetes. Conclusion: This study highlighted high-risk categories for NAFLD in diabetes, like young, obese, hypertriglyceridemia, poor glycemic control, etc. This information will help health care providers in prioritizing screening among high-risk diabetes population.

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